A rather dark, grim list of the possible ways our world would cease to exist. If the world does end any time soon, I bet it will be for reasons no. 15:
Together, the United States and Russia still have almost 19,000 active nuclear warheads. Nuclear war seems unlikely today, but a dozen years ago the demise of the Soviet Union also seemed rather unlikely. Political situations evolve; the bombs remain deadly. There is also the possibility of an accidental nuclear exchange. And a ballistic missile defense system, given current technology, will catch only a handful of stray missiles— assuming it works at all. Other types of weaponry could have global effects as well. Japan began experimenting with biological weapons after World War I, and both the United States and the Soviet Union experimented with killer germs during the cold war. Compared with atomic bombs, bioweapons are cheap, simple to produce, and easy to conceal. They are also hard to control, although that unpredictability could appeal to a terrorist organization. John Leslie, a philosopher at the University of Guelph in Ontario, points out that genetic engineering might permit the creation of "ethnic" biological weapons that are tailored to attack primarily one ethnic group (see #11).
and no. 17:
While physical health has improved in most parts of the world over the past century, mental health is getting worse. The World Health Organization estimates that 500 million people around the world suffer from a psychological disorder. By 2020, depression will likely be the second leading cause of death and lost productivity, right behind cardiovascular disease. Increasing human life spans may actually intensify the problem, because people have more years to experience the loneliness and infirmity of old age. Americans over 65 already are disproportionately likely to commit suicide. Gregory Stock, a biophysicist at the University of California at Los Angeles, believes medical science will soon allow people to live to be 200 or older. If such an extended life span becomes common, it will pose unfathomable social and psychological challenges. Perhaps 200 years of accumulated sensations will overload the human brain, leading to a new kind of insanity or fostering the spread of doomsday cults, determined to reclaim life's endpoint. Perhaps the current trends of depression and suicide among the elderly will continue. One possible solution— promoting a certain kind of mental well-being with psychoactive drugs such as Prozac— heads into uncharted waters. Researchers have no good data on the long-term effects of taking these medicines.
and no. 20:
Someone wakes up and realizes it was all a dream
Are we living a shadow existence that only fools us into thinking it is real? This age-old philosophical question still reverberates through cultural thought, from the writings of William S. Burrows to the cinematic mind games of The Matrix. Hut of the Institute of Advanced Studies sees an analogy to the danger of the collapse of the vacuum. Just as our empty space might not be the true, most stable form of the vacuum, what we call reality might not be the true, most stable form of existence. In the fourth century B.C., Taoist philosopher Chuang Tzu framed the question in more poetic terms. He described a vivid dream. In it, he was a butterfly who had no awareness of his existence as a person. When he awoke, he asked: "Was I before Chuang Tzu who dreamt about being a butterfly, or am I now a butterfly who dreams about being Chuang Tzu?"